Skip Navigation



Biometrika Advance Access published online on August 5, 2007
Biometrika, doi:10.1093/biomet/asm054
This Article
Right arrow Full Text (PDF)
Right arrow All Versions of this Article:
94/4/861    most recent
asm054v1
Right arrow References
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Martinussen, T.
Right arrow Articles by Scheike, T. H.
Right arrow Search for Related Content
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Copyright © 2007 Biometrika Trust

Article

Aalen additive hazards change-point model

Torben Martinussen

Department of Natural Sciences, The Royal Veterinary and Agricultural University, Thorvaldsensvej 40, DK-1871 Frederiksberg C, Denmark

Thomas H. Scheike

Department of Biostatistics, University of Copenhagen, Øster Farimagsgade 5 opg. B, 1014 Copenhagen K, Denmark

torbenm{at}dina.kvl.dk

ts{at}biostat.ku.dk

Received for publication 1 February 2006. Revision received 1 January 2007.
  Abstract

We study a test comparing the full Aalen additive hazards model and the change-point model, and suggest how to estimate the parameters of the change-point model. We also study a test for no change-point effect. Both tests are provided with large sample properties and a resampling method is applied to obtain p-values. The finite-sample properties of the proposed inference procedures and estimators are assessed through a simulation study. The methods are further applied to a dataset concerning myocardial infarction.

Key Words: Aalen's additive model • Change-point • Counting process • Hazard model • Survival data • Time-varying effect


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?




Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.