Skip Navigation


Biometrika Advance Access originally published online on January 24, 2009
Biometrika 2009 96(1):187-199; doi:10.1093/biomet/asn055
This Article
Right arrow Abstract Freely available
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Crump, R. K.
Right arrow Articles by Mitnik, O. A.
Right arrow Search for Related Content
Social Bookmarking
 Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

© 2009 Biometrika Trust

Articles

Dealing with limited overlap in estimation of average treatment effects

Richard K. Crump

Department of Economics, University of California, Berkeley, California 94720, U.S.A. crump{at}econ.berkeley.edu

V. Joseph Hotz

Department of Economics, Duke University, Durham, North Carolina 27708, U.S.A. hotz{at}econ.duke.edu

Guido W. Imbens

Department of Economics, Harvard University, Cambridge, Massachusetts 02138, U.S.A. imbens{at}harvard.edu

Oscar A. Mitnik

Department of Economics, University of Miami, Coral Gables, Florida 33124, U.S.A. omitnik{at}miami.edu

Received for publication 1 June 2007. Revision received 1 June 2008.

Estimation of average treatment effects under unconfounded or ignorable treatment assignment is often hampered by lack of overlap in the covariate distributions between treatment groups. This lack of overlap can lead to imprecise estimates, and can make commonly used estimators sensitive to the choice of specification. In such cases researchers have often used ad hoc methods for trimming the sample. We develop a systematic approach to addressing lack of overlap. We characterize optimal subsamples for which the average treatment effect can be estimated most precisely. Under some conditions, the optimal selection rules depend solely on the propensity score. For a wide range of distributions, a good approximation to the optimal rule is provided by the simple rule of thumb to discard all units with estimated propensity scores outside the range [0.1,0.9].

Key Words: Average treatment effect • Causality • Ignorable treatment assignment • Overlap • Propensity score • Treatment effect heterogeneity • Unconfoundedness



References

    Abadie A., Imbens G. W. Large sample properties of matching estimators for average treatment effects. Econometrica (2006) 74:235–67.[CrossRef][Web of Science]

    Connors A. F., Speroff T., Dawson N. V., Thomas C., Harrell F. E., Wagner D., Desbiens N., Goldman L., Wu A. W., Califf R. M., Fulkerson W. J., Vidaillet H., Broste S., Bellamy P., Lynn J., Knaus W. A. The effectiveness of right heart catheterization in the initial care of critically ill patients. J. Am. Med. Assoc. (1996) 276:889–97.[Abstract/Free Full Text]

    Grzybowski M., Clements E. A., Parsons L., Welch R., Tintinalli A. T., Ross M. A. Mortality benefit of immediate revascularization of acute ST-segment elevation myocardial infarction in patients with contraindications to thrombolytic therapy: A propensity analysis. J. Am. Med. Assoc. (2003) 290:1891–8.[Abstract/Free Full Text]

    Hahn J. On the role of the propensity score in efficient semiparametric estimation of average treatment effects. Econometrica (1998) 66:315–31.[CrossRef][Web of Science]

    Heckman J., Ichimura H., Todd P. Matching as an econometric evaluation estimator. Rev. Econ. Studies (1998) 65:261–94.[CrossRef][Web of Science]

    Hirano K., Imbens G. W. Estimation of causal effects using propensity score weighting: An application to data on right heart catheterization. Health Serv. Out. Res. Meth. (2001) 2:259–78.[CrossRef]

    Hirano K., Imbens G., Ridder G. Efficient estimation of average treatment effects using the estimated propensity score. Econometrica (2003) 71:1161–89.[CrossRef][Web of Science]

    Horvitz D., Thompson D. A generalization of sampling without replacement from a finite universe. J. Am. Statist. Assoc. (1952) 46:663–85.

    Imbens G. Nonparametric estimation of average treatment effects under exogeneity: A review. Rev. Econ. Statist. (2004) 86:1–29.[CrossRef][Web of Science]

    Murphy D. J., Cluff L. E. SUPPORT: Study to understand prognoses and preferences for outcomes and risks of treatments. J. Clin. Epidemiol. (1990) 43:S1–S123.[CrossRef]

    Robins J. M., Rotnitzky A. Semiparametric efficiency in multivariate regression models with missing data. J. Am. Statist. Assoc. (1995) 90:122–9.[CrossRef][Web of Science]

    Rosenbaum P. Optimal matching in observational studies. J. Am. Statist. Assoc. (1989) 84:1024–32.[CrossRef][Web of Science]

    Rosenbaum P. Observational Studies (2001) 2nd ed. New York: Springer.

    Rosenbaum P., Rubin D. The central role of the propensity score in observational studies for causal effects. Biometrika (1983) 70:41–55.[Abstract/Free Full Text]

    Rubin D. Estimating causal effects of treatments in randomized and non-randomized studies. J. Educ. Psychol. (1974) 66:688–701.[CrossRef][Web of Science]

    Rubin D. Estimating causal effects from large data sets using propensity scores. Ann. Internal Med. (1997) 127:757–63.[Abstract/Free Full Text]

    Vincent J. L., Baron J., Reinhart K., Gattinoni L., Thijs L., Webb A., Meier-Hellmann A., Nollet G., Peres-Bota D. Anemia and blood transfusion in critically ill patients. J. Am. Med. Assoc. (2002) 288:1499–507.[Abstract/Free Full Text]


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?



This Article
Right arrow Abstract Freely available
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Crump, R. K.
Right arrow Articles by Mitnik, O. A.
Right arrow Search for Related Content
Social Bookmarking
 Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?