Biometrika Advance Access originally published online on November 22, 2007
Biometrika 2007 94(4):921-937; doi:10.1093/biomet/asm066
Articles |
Empirical Likelihood Semiparametric Regression Analysis for Longitudinal Data
College of Applied Sciences, Beijing University of Technology, Beijing 100022, China lgxue{at}bjut.edu.cn
Department of Mathematics, Hong Kong Baptist University, Hong Kong, China lzhu{at}hkbu.edu.hk
Received for publication 1 November 2005. Revision received 1 March 2007.
A semiparametric regression model for longitudinal data is considered. The empirical likelihood method is used to estimate the regression coefficients and the baseline function, and to construct confidence regions and intervals. It is proved that the maximum empirical likelihood estimator of the regression coefficients achieves asymptotic efficiency and the estimator of the baseline function attains asymptotic normality when a bias correction is made. Two calibrated empirical likelihood approaches to inference for the baseline function are developed. We propose a groupwise empirical likelihood procedure to handle the inter-series dependence for the longitudinal semiparametric regression model, and employ bias correction to construct the empirical likelihood ratio functions for the parameters of interest. This leads us to prove a nonparametric version of Wilks' theorem. Compared with methods based on normal approximations, the empirical likelihood does not require consistent estimators for the asymptotic variance and bias. A simulation compares the empirical likelihood and normal-based methods in terms of coverage accuracies and average areas/lengths of confidence regions/intervals.
Key Words: Confidence region; Empirical likelihood Longitudinal data Maximum empirical likelihood estimator Semiparametric regression model
References
-
Arnold S. F. The Theory of Linear Models and Multivariate Analysis (1981) New York: John Wiley & Sons.
Bravo F. Bartlett-type adjustments for empirical discrepancy test statistics. J. Statist. Plan. Infer. (2006) 136:537–54.[CrossRef]
Chen S. X., Hall P. Smoothed empirical likelihood confidence intervals for quantiles. Ann. Statist. (1993) 21:1166–81.[CrossRef]
Chen S. X., Qin Y. S. Empirical likelihood confidence intervals for local linear smoothers. Biometrika (2000) 87:947–53.
Cheng S. C., Wei L. J. Inferences for a semiparametric model with panel data. Biometrika (2000) 87:89–97.
Corcoran S. A. Bartlett adjustments of empirical discrepancy statistics. Biometrika (1998) 85:967–72.
DiCiccio T. J., Hall P., Romano J. P. Bartlett adjustment for empirical likelihood. Ann. Statist. (1991) 19:1053–61.[CrossRef]
Fan J., Li. R. Z. New estimation and model selection procedures for semiparametric modeling in longitudinal data analysis. J. Am. Statist. Assoc. (2004) 99:710–23.[CrossRef][ISI]
Hall P., La Scala B. Methodology and algorithms of empirical likelihood. Int. Statist. Rev. (1990) 58:109–27.
He X., Zhu Z. Y., Fung W. K. Estimation in a semiparametric model for longitudinal data with unspecified dependence structure. Biometrika (2002) 89:579–90.
Hu Z. H., Wang N., Carroll R. J. Profile-kernel versus backfitting in the partially linear models for longitudinal/clustered data. Biometrika (2004) 91:251–62.
Huang J. Z., Wu C. O., Zhou L. Varying-coefficient models and basis function approximations for the analysis of repeated measurements. Biometrika (2002) 89:111–28.
Kaslow R. A., Ostrow D. G., Detels R., Phair J. P., Polk B. F., Rinaldo C. R. The multicenter AIDS cohort study: rationale, organization and selected characteristics of the participants. Am. J. Epidemiol. (1987) 126:310–8.[ISI][Medline]
Kitamura Y. Empirical likelihood method with weakly dependent processes. Ann. Statist. (1997) 25:2084–102.[CrossRef]
Kolaczyk E. D. Empirical likelihood for generalized linear models. Statist. Sinica (1994) 4:199–218.
Lin X. H., Carroll R. J. Semiparametric regression for clustered data using generalized estimating equations. J. Am. Statist. Assoc. (2001) 96:1045–56.[CrossRef][ISI]
Lin D. Y., Ying Z. Semiparametric and nonparametric regression analysis of longitudinal data (with Discussion). J. Am. Statist. Assoc. (2001) 96:103–26.[CrossRef][ISI]
Moyeed R. A., Diggle P. J. Rates of convergence in semiparametric modelling of longitudinal data. Aust. J. Statist. (1994) 36:75–93.
Nadaraya E. A. On non-parametric estimates of density function and regression curves. Theory Prob. Appl. (1965) 10:186–90.[CrossRef]
Owen A. B. Empirical likelihood ratio confidence intervals for a single function. Biometrika (1988) 75:237–49.
Owen A. B. Empirical likelihood ratio confidence regions. Ann. Statist. (1990) 18:90–120.[CrossRef]
Owen A. B. Empirical likelihood for linear models. Ann. Statist. (1991) 19:1725–47.[CrossRef]
Qin J., Lawless J. Empirical likelihood and general estimating equations. Ann. Statist. (1994) 22:300–25.[CrossRef]
Rice J. A., Silverman B. W. Estimating the mean and covariance structure nonparametrically when the data are curves. J. R. Statist. Soc. B. (1991) 53:233–43.
Shi J., Lau T. S. Empirical likelihood for partially linear models. J. Mult. Anal. (2000) 72:132–49.[CrossRef]
Stute W., Xue L. G., Zhu L. X. Empirical likelihood inference in nonlinear error in covariables models with validation data. J. Am. Statist. Assoc. (2007) 102:332–46.[CrossRef][ISI]
Wang N. Marginal nonparametric kernel regression accounting for within-subject correlation. Biometrika (2003) 90:43–52.
Wang Q. H., Linton O., Härdle W. Semiparametric regression analysis with missing response at random. J. Am. Statist. Assoc. (2004) 99:334–45.[CrossRef][ISI]
Wu C. O., Chiang C. T., Hoover D. R. Asymptotic confidence regions for kernel smoothing of a varying-coefficient model with longitudinal data. J. Am. Statist. Assoc. (1998) 93:1388–402.[CrossRef][ISI]
Xue L. G., Zhu L. X. Empirical likelihood confidence regions of the parameters in a partially linear single-index model. Sci. China A (2005) 48:1333–48.[CrossRef]
Xue L. G., Zhu L. X. Empirical likelihood for single-index model. J. Mult. Anal. (2006) 97:1295–312.[CrossRef]
Zeger S. L., Diggle P. J. Semiparametric models for longitudinal data with application to CD4 cell numbers in HIV seroconverters. Biometrics (1994) 50:689–99.[CrossRef][ISI][Medline]
Zhu L. X., Xue L. G. Empirical likelihood confidence regions in a partially linear single-index model. J. R. Statist. Soc. B (2006) 68:549–70.[CrossRef]
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