Skip Navigation

Biometrika 1993 80(1):127-139; doi:10.1093/biomet/80.1.127
© 1993 by Biometrika Trust
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by RAGHUNATHAN, T. E.
Right arrow Articles by YOICHI,
Right arrow Search for Related Content
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Analysis of binary data from a multicentre clinical trial

T. E. RAGHUNATHAN and YOICHI, II

Department of Biostatistics, SC-32, University of Washington Seattle, Washington 98195, U.S.A.

We develop several methods for estimating the treatment effect difference defined as the overall log-odds ratio of favourable response in a multicentre clinical trial comparing two treatments with binary response. A simulation study compares the bias and mean squared error of the point estimates and the exact coverage probabilities of confidence intervals obtained distributions.

Key Words: Categorical data • Conditional likelihood • EM-algorithm • Empirical Bayes • Mixed model


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Stat Methods Med ResHome page
N. Breslow, B. Leroux, and R. Platt
Approximate hierarchical modelling of discrete data in epidemiology
Statistical Methods in Medical Research, February 1, 1998; 7(1): 49 - 62.
[Abstract] [PDF]

Home page
 Med Decis MakingHome page
V. Hasselblad and D. C. McCrory
Meta-analytic Tools for Medical Decision Making: A Practical Guide
Med Decis Making, February 1, 1995; 15(1): 81 - 96.
[Abstract] [PDF]


Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.