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Biometrika 1978 65(1):141-151; doi:10.1093/biomet/65.1.141
© 1978 by Biometrika Trust
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A model for association in bivariate life tables and its application in epidemiological studies of familial tendency in chronic disease incidence

D. G. CLAYTON *

Department of Clinical Epidemiology and Social Medicine, Royal Free Hospital School of Medicine London

The application of Cox's (1972) regression model for censored survival data to epidemio-logical studies of chronic disease incidence is discussed. A related model for association in bivariate survivorship time distributions is proposed for the analysis of familial tendency in disease incidence. The possible extension of the model to general multivariate survivorship distributions is indicated.

Key Words: Censored data • Epidemiological applications • Multivariate life table • Reliability theory



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