© 1977 by Biometrika Trust
Hypothesis testing when a nuisance parameter is present only under the alternative
Applied Mathematics Division, Department of Scientific and Industrial Research Wellington, New Zealand
Suppose that the distribution of a random variable representing the outcome of an experiment depends on two parameters
and
and that we wish to test the hypothesis
= 0 against the alternative
> 0. If the distribution does not depend on
when
= 0, standard asymptotic methods such as likelihood ratio testing or C(
) testing are not directly applicable. However, these methods may, under appropriate conditions, be used to reduce the problem to one involving inference from a Gaussian process. This simplified problem is examined and a test which may be derived as a likelihood ratio test or from the union-intersection principle is introduced. Approximate expressions for the significance level and power are obtained.
Key Words: (C-alpha test Hypothesis testing Likelihood ratio test Maximum of Gaussian process Simple hypothesis Union-intersection principle
![]()
CiteULike
Connotea
Del.icio.us What's this?
This article has been cited by other articles:
![]() |
G. Zheng and H. K. T. Ng Genetic model selection in two-phase analysis for case-control association studies Biostat., July 1, 2008; 9(3): 391 - 399. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. Guidolin and A. Timmermann International asset allocation under regime switching, skew, and kurtosis preferences Rev. Financ. Stud., April 1, 2008; 21(2): 889 - 935. [Abstract] [Full Text] [PDF] |
||||
![]() |
W. Li Three lectures on case control genetic association analysis Brief Bioinform, January 1, 2008; 9(1): 1 - 13. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. Guidolin and A. Timmermann Size and Value Anomalies under Regime Shifts J. Financial Econometrics, January 1, 2008; 6(1): 1 - 48. [Abstract] [Full Text] [PDF] |
||||
![]() |
T. Martinussen and T. H. Scheike Aalen Additive Hazards Change-Point Model Biometrika, December 1, 2007; 94(4): 861 - 872. [Abstract] [PDF] |
||||
![]() |
Y. Q. Chen, J. Yang, S. Cheng, and J. B. Jackson Estimating a treatment effect with repeated measurements accounting for varying effectiveness duration Biometrika, June 1, 2007; 94(2): 387 - 402. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. Lanne A Mixture Multiplicative Error Model for Realized Volatility J. Financial Econometrics, October 1, 2006; 4(4): 594 - 616. [Abstract] [Full Text] [PDF] |
||||
![]() |
Y.-K. The, J. Fernandes, M. O. Popa, A. K. Alekov, J. Timmer, and H. Lerche Modeling of Single Noninactivating Na+ Channels: Evidence for Two Open and Several Fast Inactivated States Biophys. J., May 15, 2006; 90(10): 3511 - 3522. [Abstract] [Full Text] [PDF] |
||||
![]() |
F. Zou, J. P. Fine, J. Hu, and D. Y. Lin An Efficient Resampling Method for Assessing Genome-Wide Statistical Significance in Mapping Quantitative Trait Loci Genetics, December 1, 2004; 168(4): 2307 - 2316. [Abstract] [Full Text] [PDF] |
||||
![]() |
G. Diao, D. Y. Lin, and F. Zou Mapping Quantitative Trait Loci With Censored Observations Genetics, November 1, 2004; 168(3): 1689 - 1698. [Abstract] [Full Text] [PDF] |
||||
![]() |
S. Whelan and N. Goldman Estimating the Frequency of Events That Cause Multiple-Nucleotide Changes Genetics, August 1, 2004; 167(4): 2027 - 2043. [Abstract] [Full Text] [PDF] |
||||
![]() |
F. Zou, B. S. Yandell, and J. P. Fine Statistical Issues in the Analysis of Quantitative Traits in Combined Crosses Genetics, July 1, 2001; 158(3): 1339 - 1346. [Abstract] [Full Text] [PDF] |
||||
![]() |
H.-P. Piepho A Quick Method for Computing Approximate Thresholds for Quantitative Trait Loci Detection Genetics, January 1, 2001; 157(1): 425 - 432. [Abstract] [Full Text] |
||||
![]() |
H.-P. Piepho A Mixed-Model Approach to Mapping Quantitative Trait Loci in Barley on the Basis of Multiple Environment Data Genetics, December 1, 2000; 156(4): 2043 - 2050. [Abstract] [Full Text] |
||||






