Skip Navigation

Biometrika 1977 64(2):201-205; doi:10.1093/biomet/64.2.201
© 1977 by Biometrika Trust
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by MENDOZA, G.
Right arrow Articles by IGLEWICZ, B.
Right arrow Search for Related Content
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

A three-phase sequential model for clinical trials

GASTON MENDOZA * and BORIS IGLEWICZ

Department of Statistics, Temple University Philadelphia, Pennsylvania

The sequential version of Colton's decision-theoretic model for comparing two medical treatments is modified by considering both the patients who are in the experiment and also the patients who do not participate in the experiment, while the experiment is in progress. The consideration of the patients who do not participate in the experiment leads to major changes in the restdts. Both the minimax and Bayesian solutions are obtained and are compared with Colton's equivalent results.

Key Words: Bayesian • Deoision theory • Minimum • Sequential analysis • Three-phase olinioal trial


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?




Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.