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Biometrika 1970 57(3):471-475; doi:10.1093/biomet/57.3.471
© 1970 by Biometrika Trust
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Point and interval estimation of the common odds ratio in the combination of 2 × 2 tables with fixed marginals

JOHN J. GART

National Cancer institute Bethesda, Maryland

Consider two matched independent series of binomial variates whose odds ratios are assumed constant, i.e. {psi} = (p1iq2i)/(p2iq1i)(i =1, ..., b). Under the assumption that all marginals in each of the 2 × 2 tables are fixed, exact and approximate methods of point and interval estimation of {psi} are reviewed and derived. The methods are illustrated and compared in a numerical example.


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