Skip Navigation

Biometrika 1969 56(2):301-311; doi:10.1093/biomet/56.2.301
© 1969 by Biometrika Trust
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by DAY, N. E.
Right arrow Search for Related Content
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

A comparison of some sequential designs

N. E. DAY

The Australian National University

Various types of sequential designs are constructed for testing between the means of two normal distributions with known common variance. The designs are optimum with respects to the gain function suggested by Anscombe (1963) as being relevant to clinical trials. The offectiveness of these designs, in terms of the gain function, is compared with that of single stage designs, two-stage designs and other non-optimal but simpler sequential designs. The conclusion is reached that when the difference between the two means is expected to be large, little improvement can be made on a single stage design, but when the expected difference between the means becomes smaller, the gain in using a more sophistieated design becomes appreciable.


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?




Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.