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Biometrika 1967 54(1-2):93-108; doi:10.1093/biomet/54.1-2.93
© 1967 by Biometrika Trust
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Maximum-likelihood estimation for the mixed analysis of variance model

H. O. HARTLEY and J. N. K. RAO

Texas A and. M University

A procedure is developed for the maximum-likelihood estimation of the unknown constants and variances included in the general mixed analysis of variance model, involving fixed and random factors and interactions. The method applies to all cases where the design matrices satisfy certain conditions. The consistency and asymptotic efficiency of the estimates are discussed. Tests of hypotheses and confidence regions are derived.


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